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mouse GREM2 shRNA silencing AAV

Name 
AAV-m-GREM2-shRNA
Cat No 
shAAV-260743
Availability
6-8 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Mouse Grem2.

shAAV-260743
AAV-m-GREM2-shRNA

Ready-to-use AAV expressing shRNA for silencing of Mouse Grem2 (gremlin 2, DAN family BMP antagonist). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
Gremlin2; Prdc
Description (Vector)
Cytokine that inhibits the activity of BMP2 and BMP4 in a dose-dependent manner. Antagonized BMP4-induced suppression of progesterone production in granulosa cells (By similarity).
Gene ID
23893
Gene Name (Vector)
gremlin 2, DAN family BMP antagonist
Gene Symbol
Grem2
ORF Size (aa)
507
ORF Size (bp)
507 bp
RefSeq ID
NM_011825
RefSeq Synonyms
NM_011825, BC079905,
Species
mouse
UniGene ID
Mm.25760

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.