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human GGTLC2 Over-expression AAV

Name 
AAV-h-GGTLC2
Cat No 
AAV-209856
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human GGTLC2.

AAV-209856
AAV-h-GGTLC2

Ready-to-use AAV expressing Human GGTLC2 (gamma-glutamyltransferase light chain 2). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
GGTL4
Description (Vector)
Gamma-glutamyltransferase-1 (GGT1; MIM 612346) is a membrane-bound extracellular enzyme that cleaves gamma-glutamyl peptide bonds in glutathione and other peptides and transfers the gamma-glutamyl moiety to acceptors. Autocatalytic cleavage of the GGT1 precursor polypeptide produces a heavy chain and a light chain that associate with each other to form the functional enzyme. Light chain-only GGTs, such as GGTLC2, contain a region corresponding to the GGT1 light chain, but they lack the membrane-anchoring heavy chain region (Heisterkamp et al., 2008 (PubMed 18357469)).(supplied by OMIM, Oct 2008)
Gene ID
91227
Gene Name (Vector)
gamma-glutamyltransferase light chain 2
Gene Symbol
GGTLC2
HGNC ID
HGNC:18596
ORF Size (aa)
657
ORF Size (bp)
657 bp
RefSeq ID
NM_199127
RefSeq Synonyms
NM_199127, NM_001282879, BC069534,
Species
human
UniGene ID
Hs.632765

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.