mouse GEN1 shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Mouse Gen1.
shAAV-260037
AAV-m-GEN1-shRNA
Ready-to-use AAV expressing shRNA for silencing of Mouse Gen1 (GEN1, Holliday junction 5′ flap endonuclease). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
5830483C08Rik
Description (Vector)
Endonuclease which resolves Holliday junctions by the introduction of symmetrically related cuts across the junction point, to produce nicked duplex products in which the nicks can be readily ligated. Four-way DNA intermediates, also known as Holliday junctions, are formed during homologous recombination and DNA repair, and their resolution is necessary for proper chromosome segregation.
Gene ID
209334
Gene Name (Vector)
GEN1, Holliday junction 5' flap endonuclease
Gene Symbol
Gen1
ORF Size (aa)
2727
ORF Size (bp)
2727 bp
RefSeq ID
NM_177331
RefSeq Synonyms
NM_177331, BC138158, BC138157, BC090653,
Species
mouse
UniGene ID
Mm.215295
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.
