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mouse FLNC shRNA silencing AAV

Name 
AAV-m-FLNC-shRNA
Cat No 
shAAV-259471
Availability
4-5 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Mouse Flnc.

shAAV-259471
AAV-m-FLNC-shRNA

Ready-to-use AAV expressing shRNA for silencing of Mouse Flnc (filamin C, gamma). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
80
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
1110055E19Rik; ABP-280; ABPL; Fln2
Description (Vector)
Muscle-specific filamin, which plays a central role in muscle cells, probably by functioning as a large actin-cross-linking protein. May be involved in reorganizing the actin cytoskeleton in response to signaling events, and may also display structural functions at the Z lines in muscle cells. Critical for normal myogenesis and for maintaining the structural integrity of the muscle fibers.
Gene ID
68794
Gene Name (Vector)
filamin C, gamma
Gene Symbol
Flnc
ORF Size (aa)
8178
ORF Size (bp)
8178 bp
RefSeq ID
NM_001081185
RefSeq Synonyms
NM_001311074, NM_001081185, BC172720, BC158128, BC156519, BC151097,
Species
mouse
UniGene ID
Mm.39046

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.