mouse FBXW4 shRNA silencing AAV

Name 
AAV-m-FBXW4-shRNA
Cat No 
shAAV-259271
Availability
4-5 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Mouse Fbxw4.

shAAV-259271
AAV-m-FBXW4-shRNA

Ready-to-use AAV expressing shRNA for silencing of Mouse Fbxw4 (F-box and WD-40 domain protein 4). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
90
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
Dac; dactylin; dactylyn; Fbw4; SHFM3; SHSF3
Description (Vector)
Probably recognizes and binds to some phosphorylated proteins and promotes their ubiquitination and degradation. Likely to be involved in key signaling pathways crucial for normal limb development. May participate in Wnt signaling.
Gene ID
30838
Gene Name (Vector)
F-box and WD-40 domain protein 4
Gene Symbol
Fbxw4
ORF Size (aa)
1233
ORF Size (bp)
1233 bp
RefSeq ID
NM_013907
RefSeq Synonyms
NM_013907, BC027031,
Species
mouse
UniGene ID
Mm.254739

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.