mouse FBXL21 shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Mouse Fbxl21.
shAAV-259208
AAV-m-FBXL21-shRNA
Ready-to-use AAV expressing shRNA for silencing of Mouse Fbxl21 (F-box and leucine-rich repeat protein 21). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
D630045D17Rik; FBL3B; FBXL3B; Psttm
Description (Vector)
Substrate-recognition component of some SCF (SKP1-CUL1-F-box protein)-type E3 ubiquitin ligase complex involved in circadian pacemaker function. The SCF(FBXL21) complex acts by mediating ubiquitination and subsequent degradation of CRY1. Probable clock-controlled protein that plays a specific role in suprachiasmatic nucleus, SCN and pacemaker function (By similarity).
Gene ID
213311
Gene Name (Vector)
F-box and leucine-rich repeat protein 21
Gene Symbol
Fbxl21
ORF Size (aa)
1305
ORF Size (bp)
1305 bp
RefSeq ID
NM_178674
RefSeq Synonyms
NM_178674, NM_001346732, BC138941, BC138940,
Species
mouse
UniGene ID
Mm.233904
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.