mouse FBLN1 shRNA silencing AAV

Name
AAV-m-FBLN1-shRNA

Cat No
shAAV-259185

Availability
4-5 weeks

This is an AAV expressing shRNA for silencing of Mouse Fbln1.

shAAV-259185

AAV-m-FBLN1-shRNA

Ready-to-use AAV expressing shRNA for silencing of Mouse Fbln1 (fibulin 1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

shRNA Knockdown (%)

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Description (Vector)

Incorporated into fibronectin-containing matrix fibers. May play a role in cell adhesion and migration along protein fibers within the extracellular matrix (ECM). Could be important for certain developmental processes and contribute to the supramolecular organization of ECM architecture, in particular to those of basement membranes. Has been implicated in a role in cellular transformation and tumor invasion, it appears to be a tumor suppressor. May play a role in haemostasis and thrombosis owing to its ability to bind fibrinogen and incorporate into clots. Could play a significant role in modulating the neurotrophic activities of APP, particularly soluble APP.

Gene ID

14114

Gene Name (Vector)

fibulin 1

Gene Symbol

Fbln1

ORF Size (aa)

2058

ORF Size (bp)

2058 bp

RefSeq ID

NM_010180

RefSeq Synonyms

NM_010180, NM_001347088, BC007140,

Species

mouse

UniGene ID

Mm.297992

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.