mouse FAS shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Mouse Fas.
shAAV-259165
AAV-m-FAS-shRNA
Ready-to-use AAV expressing shRNA for silencing of Mouse Fas (Fas (TNF receptor superfamily member 6)). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
AI196731; APO1; APT1; CD95; lpr; TNFR6; Tnfrsf6
Description (Vector)
Receptor for TNFSF6/FASLG. The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis. FAS-mediated apoptosis may have a role in the induction of peripheral tolerance, in the antigen-stimulated suicide of mature T-cells, or both. The secreted isoforms 2 to 6 block apoptosis (in vitro).
Gene ID
14102
Gene Name (Vector)
Fas (TNF receptor superfamily member 6)
Gene Symbol
Fas
ORF Size (aa)
984
RefSeq ID
NM_007987
RefSeq Synonyms
NM_007987, NM_001146708, BC061160,
Species
mouse
UniGene ID
Mm.1626
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.