mouse FAM20B shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Mouse Fam20b.
shAAV-259046
AAV-m-FAM20B-shRNA
Ready-to-use AAV expressing shRNA for silencing of Mouse Fam20b (family with sequence similarity 20, member B). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
C530043G21Rik; mKIAA0475
Description (Vector)
Responsible for the 2-O-phosphorylation of xylose in the glycosaminoglycan-protein linkage region of proteoglycans thereby regulating the amount of mature GAG chains. Sulfated glycosaminoglycans (GAGs), including heparan sulfate and chondroitin sulfate, are synthesized on the so-called common GAG-protein linkage region (GlcUAbeta1-3Galbeta1-3Galbeta1-4Xylbeta1-O-Ser) of core proteins, which is formed by the stepwise addition of monosaccharide residues by the respective specific glycosyltransferases. Xylose 2-o-phosphorylation may influence the catalytic activity of B3GAT3 (GlcAT-I) which completes the precursor tetrasaccharide of GAG-protein linkage regions on which the repeating disaccharide region is synthesized.
Gene ID
215015
Gene Name (Vector)
family with sequence similarity 20, member B
Gene Symbol
Fam20b
ORF Size (aa)
1230
ORF Size (bp)
1230 bp
RefSeq ID
NM_145413
RefSeq Synonyms
NM_145413, BC031473, BC024412, BC023737, BC019381,
Species
mouse
UniGene ID
Mm.229107
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.