human GCDH Over-expression AAV

Name 
AAV-h-GCDH
Cat No 
AAV-209733
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human GCDH.

AAV-209733
AAV-h-GCDH

Ready-to-use AAV expressing Human GCDH (glutaryl-CoA dehydrogenase). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
ACAD5; GCD
Description (Vector)
GCDH belongs to the acyl-CoA dehydrogenase family. It catalyzes the oxidative decarboxylation of glutaryl-CoA to crotonyl-CoA and CO(2) in the degradative pathway of L-lysine, L-hydroxylysine, and L-tryptophan metabolism. It uses electron transfer flavoprotein as its electron acceptor. The enzyme exists in the mitochondrial matrix as a homotetramer of 45-kD subunits. Alternatively spliced transcript variants encoding different isoforms have been identified.
Gene ID
2639
Gene Name (Vector)
glutaryl-CoA dehydrogenase
Gene Symbol
GCDH
HGNC ID
HGNC:4189
ORF Size (aa)
1317
ORF Size (bp)
1317 bp
RefSeq ID
NM_013976
RefSeq Synonyms
NM_013976, NM_000159, BC002579,
Species
human
UniGene ID
Hs.532699

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.