mouse MMS22L shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Mouse Mms22l.
shAAV-258853
AAV-m-MMS22L-shRNA
Ready-to-use AAV expressing shRNA for silencing of Mouse Mms22l (MMS22-like, DNA repair protein). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
F730047E07Rik; Gm134
Description (Vector)
Component of the MMS22L-TONSL complex, a complex that stimulates the recombination-dependent repair of stalled or collapsed replication forks. The MMS22L-TONSL complex is required to maintain genome integrity during DNA replication by promoting homologous recombination-mediated repair of replication fork-associated double-strand breaks. It may act by mediating the assembly of RAD51 filaments on ssDNA.
Gene ID
212377
Gene Name (Vector)
MMS22-like, DNA repair protein
Gene Symbol
Mms22l
ORF Size (aa)
2889
ORF Size (bp)
2889 bp
RefSeq ID
NM_199467
RefSeq Synonyms
NM_199467, BC145028, BC137910,
Species
mouse
UniGene ID
Mm.120919
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.