mouse F12 shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Mouse F12.
shAAV-258831
AAV-m-F12-shRNA
Ready-to-use AAV expressing shRNA for silencing of Mouse F12 (coagulation factor XII (Hageman factor)). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
FXII; HAF
Description (Vector)
Factor XII is a serum glycoprotein that participates in the initiation of blood coagulation, fibrinolysis, and the generation of bradykinin and angiotensin. Prekallikrein is cleaved by factor XII to form kallikrein, which then cleaves factor XII first to alpha-factor XIIa and then trypsin cleaves it to beta-factor XIIa. Alpha-factor XIIa activates factor XI to factor XIa.
Gene ID
58992
Gene Name (Vector)
coagulation factor XII (Hageman factor)
Gene Symbol
F12
ORF Size (aa)
1794
ORF Size (bp)
1794 bp
RefSeq ID
NM_021489
RefSeq Synonyms
NM_021489, BC057921,
Species
mouse
UniGene ID
Mm.42224
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.