mouse EWSR1 shRNA silencing AAV

Name
AAV-m-EWSR1-shRNA

Cat No
shAAV-258762

Availability
4-5 weeks

This is an AAV expressing shRNA for silencing of Mouse Ewsr1.

shAAV-258762

AAV-m-EWSR1-shRNA

Ready-to-use AAV expressing shRNA for silencing of Mouse Ewsr1 (Ewing sarcoma breakpoint region 1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

shRNA Knockdown (%)

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

Ews; Ewsh

Description (Vector)

Might normally function as a repressor. EWS-fusion-proteins (EFPS) may play a role in the tumorigenic process. They may disturb gene expression by mimicking, or interfering with the normal function of CTD-POLII within the transcription initiation complex. They may also contribute to an aberrant activation of the fusion protein target genes.

Gene ID

14030

Gene Name (Vector)

Ewing sarcoma breakpoint region 1

Gene Symbol

Ewsr1

ORF Size (aa)

1971

ORF Size (bp)

1971 bp

RefSeq ID

NM_007968

RefSeq Synonyms

NM_007968, NM_001283063, NM_001283062, NM_001283061, BC068226,

Species

mouse

UniGene ID

Mm.142822

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.