mouse ESRRA shRNA silencing AAV

Name 
AAV-m-ESRRA-shRNA
Cat No 
shAAV-258720
Availability
4-5 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Mouse Esrra.

shAAV-258720
AAV-m-ESRRA-shRNA

Ready-to-use AAV expressing shRNA for silencing of Mouse Esrra (estrogen related receptor, alpha). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
80
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
Err1; ERRalpha; Estrra; Nr3b1
Description (Vector)
Binds to an ERR-alpha response element (ERRE) containing a single consensus half-site, 5'-TNAAGGTCA-3'. Can bind to the medium-chain acyl coenzyme A dehydrogenase (MCAD) response element NRRE-1 and may act as an important regulator of MCAD promoter. Binds to the C1 region of the lactoferrin gene promoter. Requires dimerization and the coactivator, PGC-1A, for full activity. The ERRalpha/PGC1alpha complex is a regulator of energy metabolism.
Gene ID
26379
Gene Name (Vector)
estrogen related receptor, alpha
Gene Symbol
Esrra
ORF Size (aa)
1269
ORF Size (bp)
1269 bp
RefSeq ID
NM_007953
RefSeq Synonyms
NM_007953, BC171958, BC138586,
Species
mouse
UniGene ID
Mm.386776

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.