mouse EIF4E shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Mouse Eif4e.
shAAV-258230
AAV-m-EIF4E-shRNA
Ready-to-use AAV expressing shRNA for silencing of Mouse Eif4e (eukaryotic translation initiation factor 4E). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
EG668879; eIF-4E; Eif4e-ps; If4e
Description (Vector)
Its translation stimulation activity is repressed by binding to the complex CYFIP1-FMR1 (By similarity). Recognizes and binds the 7-methylguanosine-containing mRNA cap during an early step in the initiation of protein synthesis and facilitates ribosome binding by inducing the unwinding of the mRNAs secondary structures. Component of the CYFIP1-EIF4E-FMR1 complex which binds to the mRNA cap and mediates translational repression. In the CYFIP1-EIF4E-FMR1 complex this subunit mediates the binding to the mRNA cap.
Gene ID
13684
Gene Name (Vector)
eukaryotic translation initiation factor 4E
Gene Symbol
Eif4e
ORF Size (aa)
654
RefSeq ID
NM_007917
RefSeq Synonyms
NM_007917, NM_001313980, BC085087, BC010759,
Species
mouse
UniGene ID
Mm.3941
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.