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mouse EIF2C1 shRNA silencing AAV

Name 
AAV-m-EIF2C1-shRNA
Cat No 
shAAV-258191
Availability
4-5 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Mouse Ago1.

shAAV-258191
AAV-m-EIF2C1-shRNA

Ready-to-use AAV expressing shRNA for silencing of Mouse Ago1 (argonaute RISC catalytic subunit 1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
60
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
Eif2c1
Description (Vector)
Required for RNA-mediated gene silencing (RNAi). Binds to short RNAs such as microRNAs (miRNAs) or short interfering RNAs (siRNAs), and represses the translation of mRNAs which are complementary to them. Lacks endonuclease activity and does not appear to cleave target mRNAs. Also required for transcriptional gene silencing (TGS) of promoter regions which are complementary to bound short antigene RNAs (agRNAs).
Gene ID
236511
Gene Name (Vector)
argonaute RISC catalytic subunit 1
Gene Symbol
Ago1
ORF Size (aa)
2574
ORF Size (bp)
2574 bp
RefSeq ID
NM_153403
RefSeq Synonyms
NM_153403, NM_001317174, NM_001317173, BC129914,
Species
mouse
UniGene ID
Mm.30800

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.