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mouse EFTUD1 shRNA silencing AAV

Name 
AAV-m-EFTUD1-shRNA
Cat No 
shAAV-257828
Availability
4-5 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Mouse Efl1.

shAAV-257828
AAV-m-EFTUD1-shRNA

Ready-to-use AAV expressing shRNA for silencing of Mouse Efl1 (elongation factor like GPTase 1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
80
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
4932434J20Rik; 6030468D11Rik; AI451340; AU019507; AU022896; D7Ertd791e; Eftud1
Description (Vector)
Involved in the biogenesis of the 60S ribosomal subunit and translational activation of ribosomes. Together with SBDS, triggers the GTP-dependent release of EIF6 from 60S pre-ribosomes in the cytoplasm, thereby activating ribosomes for translation competence by allowing 80S ribosome assembly and facilitating EIF6 recycling to the nucleus, where it is required for 60S rRNA processing and nuclear export. Has low intrinsic GTPase activity. GTPase activity is increased by contact with 60S ribosome subunits.
Gene ID
101592
Gene Name (Vector)
elongation factor like GPTase 1
Gene Symbol
Efl1
ORF Size (aa)
3384
ORF Size (bp)
3384 bp
RefSeq ID
NM_175317
RefSeq Synonyms
NM_175317, NM_001159672, BC045616,
Species
mouse
UniGene ID
Mm.238020

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.