mouse EFNA3 shRNA silencing AAV

Name
AAV-m-EFNA3-shRNA

Cat No
shAAV-257814

Availability
4-5 weeks

This is an AAV expressing shRNA for silencing of Mouse Efna3.

shAAV-257814

AAV-m-EFNA3-shRNA

Ready-to-use AAV expressing shRNA for silencing of Mouse Efna3 (ephrin A3). Available with optional GFP reporter or cell-specific promoter.

Request a Quote

Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

shRNA Knockdown (%)

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

AW494418; EFL-2; Ehk1-L; Epl3; LERK-3

Description (Vector)

Cell surface GPI-bound ligand for Eph receptors, a family of receptor tyrosine kinases which are crucial for migration, repulsion and adhesion during neuronal, vascular and epithelial development. Binds promiscuously Eph receptors residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells. The signaling pathway downstream of the receptor is referred to as forward signaling while the signaling pathway downstream of the ephrin ligand is referred to as reverse signaling (By similarity).

Gene ID

13638

Gene Name (Vector)

ephrin A3

Gene Symbol

Efna3

ORF Size (aa)

693

ORF Size (bp)

693 bp

RefSeq ID

NM_010108

RefSeq Synonyms

NM_010108, BC125003, BC107002,

Species

mouse

UniGene ID

Mm.331159

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.