mouse E2F2 shRNA silencing AAV

Name
AAV-m-E2F2-shRNA

Cat No
shAAV-257650

Availability
6-8 weeks

This is an AAV expressing shRNA for silencing of Mouse E2f2.

shAAV-257650

AAV-m-E2F2-shRNA

Ready-to-use AAV expressing shRNA for silencing of Mouse E2f2 (E2F transcription factor 2). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

E2F-2

Description (Vector)

Transcription activator that binds DNA cooperatively with DP proteins through the E2 recognition site, 5'-TTTC[CG]CGC-3' found in the promoter region of a number of genes whose products are involved in cell cycle regulation or in DNA replication. The DRTF1/E2F complex functions in the control of cell-cycle progression from g1 to s phase. E2F-2 binds specifically to RB1 protein, in a cell-cycle dependent manner.

Gene ID

242705

Gene Name (Vector)

E2F transcription factor 2

Gene Symbol

E2f2

ORF Size (aa)

1332

ORF Size (bp)

1332 bp

RefSeq ID

NM_177733

RefSeq Synonyms

NM_177733, NM_001305399, BC062101,

Species

mouse

UniGene ID

Mm.307932

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.