mouse DNAJC3 shRNA silencing AAV

Name 
AAV-m-DNAJC3-shRNA
Cat No 
shAAV-257315
Availability
4-5 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Mouse Dnajc3.

shAAV-257315
AAV-m-DNAJC3-shRNA

Ready-to-use AAV expressing shRNA for silencing of Mouse Dnajc3 (DnaJ heat shock protein family (Hsp40) member C3). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
90
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
AA408985; AU067833; Dnajc3a; Dnajc3b; mp58; p58; p58IPK; Prkri
Description (Vector)
Involved in the unfolded protein response (UPR) during ER stress. Co-chaperone of HSPA8/HSC70, it stimulates its ATPase activity. May inhibit both the autophosphorylation of EIF2AK2/PKR and the ability of EIF2AK2 to catalyze phosphorylation of the EIF2A. May inhibit EIF2AK3/PERK activity.
Gene ID
100037258
Gene Name (Vector)
DnaJ heat shock protein family (Hsp40) member C3
Gene Symbol
Dnajc3
ORF Size (aa)
1515
ORF Size (bp)
1515 bp
RefSeq ID
NM_008929
RefSeq Synonyms
NM_008929, BC013766,
Species
mouse
UniGene ID
Mm.12616

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.