mouse DLG2 shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Mouse Dlg2.
shAAV-257221
AAV-m-DLG2-shRNA
Ready-to-use AAV expressing shRNA for silencing of Mouse Dlg2 (discs, large homolog 2 (Drosophila)). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
A330103J02Rik; B230218P12Rik; B330007M19Rik; Dlgh2; Gm1197; Gm21505; PSD93
Description (Vector)
Required for perception of chronic pain through NMDA receptor signaling. Regulates surface expression of NMDA receptors in dorsal horn neurons of the spinal cord. Interacts with the cytoplasmic tail of NMDA receptor subunits as well as inward rectifying potassium channels. Involved in regulation of synaptic stability at cholinergic synapses. Part of the postsynaptic protein scaffold of excitatory synapses (By similarity).
Gene ID
23859
Gene Name (Vector)
discs, large homolog 2 (Drosophila)
Gene Symbol
Dlg2
ORF Size (aa)
2556
ORF Size (bp)
2556 bp
RefSeq ID
NM_011807
RefSeq Synonyms
NM_011807, NM_001243047, NM_001243046, BC146460, BC140302,
Species
mouse
UniGene ID
Mm.257035
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.