mouse DGAT2 shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Mouse Dgat2.
shAAV-257109
AAV-m-DGAT2-shRNA
Ready-to-use AAV expressing shRNA for silencing of Mouse Dgat2 (diacylglycerol O-acyltransferase 2). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
0610010B06Rik; ARAT; DGAT-2
Description (Vector)
Essential acyltransferase that catalyzes the terminal and only committed step in triacylglycerol synthesis by using diacylglycerol and fatty acyl CoA as substrates. Required for synthesis and storage of intracellular triglycerides. Probably plays a central role in cytosolic lipid accumulation. In liver, is primarily responsible for incorporating endogenously synthesized fatty acids into triglycerides (By similarity). Functions also as an acyl-CoA retinol acyltransferase (ARAT).
Gene ID
67800
Gene Name (Vector)
diacylglycerol O-acyltransferase 2
Gene Symbol
Dgat2
ORF Size (aa)
1167
ORF Size (bp)
1167 bp
RefSeq ID
NM_026384
RefSeq Synonyms
NM_026384, BC043447,
Species
mouse
UniGene ID
Mm.477728
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.