mouse DERL3 shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Mouse Derl3.
shAAV-257100
AAV-m-DERL3-shRNA
Ready-to-use AAV expressing shRNA for silencing of Mouse Derl3 (Der1-like domain family, member 3). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
1810006I20Rik; 1810063P04Rik; derlin-3; IZP6
Description (Vector)
Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal glycoproteins, but not that of misfolded nonglycoproteins. May act by forming a channel that allows the retrotranslocation of misfolded glycoproteins into the cytosol where they are ubiquitinated and degraded by the proteasome. May mediate the interaction between VCP and the degradation substrate.
Gene ID
70377
Gene Name (Vector)
Der1-like domain family, member 3
Gene Symbol
Derl3
ORF Size (aa)
687
ORF Size (bp)
687 bp
RefSeq ID
NM_024440
RefSeq Synonyms
NM_024440, BC115467, BC115466,
Species
mouse
UniGene ID
Mm.275878
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.