mouse D2ERTD750E shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Mouse Knstrn.
shAAV-256682
AAV-m-D2ERTD750E-shRNA
Ready-to-use AAV expressing shRNA for silencing of Mouse Knstrn (kinetochore-localized astrin/SPAG5 binding). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
1700025D04Rik; C15orf23; D2Ertd750e; SKAP; Traf4af1
Description (Vector)
Essential component of the mitotic spindle required for normal chromosome segregation and progression into anaphase. Promotes the metaphase-to-anaphase transition and is required for chromosome alignment, normal timing of sister chromatid segregation, and maintenance of spindle pole architecture. The astrin (SPAG5)-kinastrin (SKAP) complex promotes stable microtubule-kinetochore attachments.
Gene ID
51944
Gene Name (Vector)
kinetochore-localized astrin/SPAG5 binding
Gene Symbol
Knstrn
ORF Size (aa)
705
ORF Size (bp)
705 bp
RefSeq ID
NM_026412
RefSeq Synonyms
NM_026412, BC031709,
Species
mouse
UniGene ID
Mm.252695
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.