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mouse CYBB shRNA silencing AAV

Name 
AAV-m-CYBB-shRNA
Cat No 
shAAV-256443
Availability
6-8 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Mouse Cybb.

shAAV-256443
AAV-m-CYBB-shRNA

Ready-to-use AAV expressing shRNA for silencing of Mouse Cybb (cytochrome b-245, beta polypeptide). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
C88302; Cgd; CGD91-phox; Cyd; gp91-1; gp91phox; Nox2
Description (Vector)
Critical component of the membrane-bound oxidase of phagocytes that generates superoxide. It is the terminal component of a respiratory chain that transfers single electrons from cytoplasmic NADPH across the plasma membrane to molecular oxygen on the exterior. Also functions as a voltage-gated proton channel that mediates the H(+) currents of resting phagocytes. It participates in the regulation of cellular pH and is blocked by zinc.
Gene ID
13058
Gene Name (Vector)
cytochrome b-245, beta polypeptide
Gene Symbol
Cybb
ORF Size (aa)
1713
ORF Size (bp)
1713 bp
RefSeq ID
NM_007807
RefSeq Synonyms
NM_007807, BC071229,
Species
mouse
UniGene ID
Mm.200362

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.