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mouse CTDSP2 shRNA silencing AAV

Name 
AAV-m-CTDSP2-shRNA
Cat No 
shAAV-256298
Availability
4-5 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Mouse Ctdsp2.

shAAV-256298
AAV-m-CTDSP2-shRNA

Ready-to-use AAV expressing shRNA for silencing of Mouse Ctdsp2 (CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 2). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
90
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
AI586070; D10Ertd73e; OS-4; OS4; SCP2
Description (Vector)
Preferentially catalyzes the dephosphorylation of 'Ser-5' within the tandem 7 residues repeats in the C-terminal domain (CTD) of the largest RNA polymerase II subunit POLR2A. Negatively regulates RNA polymerase II transcription, possibly by controlling the transition from initiation/capping to processive transcript elongation. Recruited by REST to neuronal genes that contain RE-1 elements, leading to neuronal gene silencing in non-neuronal cells. May contribute to the development of sarcomas.
Gene ID
52468
Gene Name (Vector)
CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 2
Gene Symbol
Ctdsp2
ORF Size (aa)
360
RefSeq ID
NM_146012
RefSeq Synonyms
NM_146012, NM_001113470, BC085142, BC025650,
Species
mouse
UniGene ID
Mm.29490

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.