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mouse ZRANB1 shRNA silencing AAV

Name 
AAV-m-ZRANB1-shRNA
Cat No 
shAAV-256290
Availability
4-5 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Mouse Zranb1.

shAAV-256290
AAV-m-ZRANB1-shRNA

Ready-to-use AAV expressing shRNA for silencing of Mouse Zranb1 (zinc finger, RAN-binding domain containing 1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
90
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
9330160G10Rik; D7Wsu87e; Gm1956; Trabid
Description (Vector)
Positive regulator of the Wnt signaling pathway that specifically cleaves 'Lys-63'-linked ubiquitin chains. Acts by deubiquitinating APC protein, a negative regulator of Wnt-mediated transcription. Plays a role in the regulation of cell morphology and cytoskeletal organization. Required in the stress fiber dynamics and cell migration. May also modulate TNF-alpha signaling.
Gene ID
360216
Gene Name (Vector)
zinc finger, RAN-binding domain containing 1
Gene Symbol
Zranb1
ORF Size (aa)
2127
ORF Size (bp)
2127 bp
RefSeq ID
NM_207302
RefSeq Synonyms
NM_207302, BC168391,
Species
mouse
UniGene ID
Mm.389984

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.