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mouse CORIN shRNA silencing AAV

Name 
AAV-m-CORIN-shRNA
Cat No 
shAAV-255943
Availability
6-8 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Mouse Corin.

shAAV-255943
AAV-m-CORIN-shRNA

Ready-to-use AAV expressing shRNA for silencing of Mouse Corin (corin). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
AV273130; Lrp4
Description (Vector)
Serine-type endopeptidase involved in atrial natriuretic peptide hormone (NPPA) processing. Converts through proteolytic cleavage the non-functional propeptide NPPA into the active hormone, thereby regulating blood pressure in heart and promoting natriuresis, diuresis and vasodilation. Proteolytic cleavage of pro-NPPA also plays a role in female pregnancy by promoting trophoblast invasion and spiral artery remodeling in uterus. Also acts as a regulator of sodium reabsorption in kidney. May also process pro-NPPB the B-type natriuretic peptide|Function: Isoform 2: has weaker endopeptidase activity compared to isoform 1.
Gene ID
53419
Gene Name (Vector)
corin
Gene Symbol
Corin
ORF Size (aa)
3342
ORF Size (bp)
3342 bp
RefSeq ID
NM_016869
RefSeq Synonyms
NM_016869, NM_001122756, BC145243, BC138340, BC138339, BC093485,
Species
mouse
UniGene ID
Mm.332425

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.