mouse COMMD1 shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Mouse Commd1.
shAAV-255883
AAV-m-COMMD1-shRNA
Ready-to-use AAV expressing shRNA for silencing of Mouse Commd1 (COMM domain containing 1). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
AI256843; Murr1; U2/Mu
Description (Vector)
Promotes ubiquitination of NF-kappa-B subunit RELA and its subsequent proteasomal degradation. Down-regulates NF-kappa-B activity. Down-regulates SOD1 activity by interfering with its homodimerization. Plays a role in copper ion homeostasis. Can bind one copper ion per monomer. May function to facilitate biliary copper excretion within hepatocytes.
Gene ID
17846
Gene Name (Vector)
COMM domain containing 1
Gene Symbol
Commd1
ORF Size (aa)
567
RefSeq ID
NM_144514
RefSeq Synonyms
NM_144514, BC132085, BC132083,
Species
mouse
UniGene ID
Mm.451238
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.