human FXN Over-expression AAV

Name 
AAV-h-FXN
Cat No 
AAV-209435
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human FXN.

AAV-209435
AAV-h-FXN

Ready-to-use AAV expressing Human FXN (frataxin). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
CyaY; FA; FARR; FRDA; X25
Description (Vector)
This nuclear gene encodes a mitochondrial protein which belongs to FRATAXIN family. The protein functions in regulating mitochondrial iron transport and respiration. The expansion of intronic trinucleotide repeat GAA results in Friedreich ataxia. Alternative splicing results in multiple transcript variants.
Gene ID
2395
Gene Name (Vector)
frataxin
Gene Symbol
FXN
HGNC ID
HGNC:3951
ORF Size (aa)
633
RefSeq ID
NM_000144
RefSeq Synonyms
NM_181425, NM_001161706, NM_000144, BC048097, BC023633,
Species
human
UniGene ID
Hs.29978

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.