mouse CLDN16 shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Mouse Cldn16.
shAAV-255591
AAV-m-CLDN16-shRNA
Ready-to-use AAV expressing shRNA for silencing of Mouse Cldn16 (claudin 16). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
claudin-16; PCLN1
Description (Vector)
Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity. Involved in paracellular magnesium reabsorption. Required for a selective paracellular conductance. May form, alone or in partnership with other constituents, an intercellular pore permitting paracellular passage of magnesium and calcium ions down their electrochemical gradients. Alternatively, it could be a sensor of magnesium concentration that could alter paracellular permeability mediated by other factors.
Gene ID
114141
Gene Name (Vector)
claudin 16
Gene Symbol
Cldn16
ORF Size (aa)
708
RefSeq ID
NM_053241
RefSeq Synonyms
NM_053241, BC115575, BC115574,
Species
mouse
UniGene ID
Mm.275205
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.