mouse CFB shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Mouse Cfb.
shAAV-255325
AAV-m-CFB-shRNA
Ready-to-use AAV expressing shRNA for silencing of Mouse Cfb (complement factor B). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
AI195813; AI255840; B; Bf; C2; Fb; H2-Bf
Description (Vector)
Factor B which is part of the alternate pathway of the complement system is cleaved by factor D into 2 fragments: Ba and Bb. Bb, a serine protease, then combines with complement factor 3b to generate the C3 or C5 convertase. It has also been implicated in proliferation and differentiation of preactivated B-lymphocytes, rapid spreading of peripheral blood monocytes, stimulation of lymphocyte blastogenesis and lysis of erythrocytes. Ba inhibits the proliferation of preactivated B-lymphocytes.
Gene ID
14962
Gene Name (Vector)
complement factor B
Gene Symbol
Cfb
ORF Size (aa)
2286
ORF Size (bp)
2286 bp
RefSeq ID
NM_008198
RefSeq Synonyms
NM_008198, NM_001142706, BC005451,
Species
mouse
UniGene ID
Mm.653
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.