mouse CEBPB shRNA silencing AAV

Name
AAV-m-CEBPB-shRNA

Cat No
shAAV-255244

Availability
4-5 weeks

This is an AAV expressing shRNA for silencing of Mouse Cebpb.

shAAV-255244

AAV-m-CEBPB-shRNA

Ready-to-use AAV expressing shRNA for silencing of Mouse Cebpb (CCAAT/enhancer binding protein (C/EBP), beta). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

shRNA Knockdown (%)

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

C/EBPbeta; CRP2; IL-6DBP; LAP; LIP; NF-IL6; NF-M; Nfil6

Description (Vector)

Important transcriptional activator in the regulation of genes involved in immune and inflammatory responses. Specifically binds to an IL-1 response element in the IL-6 gene. NF-IL6 also binds to regulatory regions of several acute-phase and cytokines genes. It probably plays a role in the regulation of acute-phase reaction, inflammation and hemopoiesis. The consensus recognition site is 5'-T[TG]NNGNAA[TG]-3'. Functions in brown adipose tissue (BAT) differentiation (By similarity).

Gene ID

12608

Gene Name (Vector)

CCAAT/enhancer binding protein (C/EBP), beta

Gene Symbol

Cebpb

ORF Size (aa)

891

ORF Size (bp)

891 bp

RefSeq ID

NM_009883

RefSeq Synonyms

NM_009883, NM_001287739, NM_001287738, BC160327,

Species

mouse

UniGene ID

Mm.439656

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.