mouse CDKN1B shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Mouse Cdkn1b.
shAAV-255188
AAV-m-CDKN1B-shRNA
Ready-to-use AAV expressing shRNA for silencing of Mouse Cdkn1b (cyclin-dependent kinase inhibitor 1B). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
AA408329; AI843786; Kip1; p27; p27Kip1
Description (Vector)
Important regulator of cell cycle progression. Involved in G1 arrest. Potent inhibitor of cyclin E- and cyclin A-CDK2 complexes. Forms a complex with cyclin type D-CDK4 complexes and is involved in the assembly, stability, and modulation of CCND1-CDK4 complex activation. Acts either as an inhibitor or an activator of cyclin type D-CDK4 complexes depending on its phosphorylation state and/or stoichometry.
Gene ID
12576
Gene Name (Vector)
cyclin-dependent kinase inhibitor 1B
Gene Symbol
Cdkn1b
ORF Size (aa)
594
RefSeq ID
NM_009875
RefSeq Synonyms
NM_009875, BC014296,
Species
mouse
UniGene ID
Mm.2958
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.