mouse CD80 shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Mouse Cd80.
shAAV-255048
AAV-m-CD80-shRNA
Ready-to-use AAV expressing shRNA for silencing of Mouse Cd80 (CD80 antigen). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
activation B7-1 antigen; B7; B7 protein; B71; CD antigen CD80; Cd28l; Ly53; Ly-53; MIC17; T-lymphocyte activation antigen CD80; TSA1
Description (eCommerce)
CD80 is a membrane receptor involved in the costimulatory signal essential for T-lymphocyte activation. T-cell proliferation and cytokine production is induced by the binding of CD28, binding to CTLA-4 has opposite effects and inhibits T-cell activation. [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/P33681].
Description (Vector)
Involved in the costimulatory signal essential for T-lymphocyte activation. T-cell proliferation and cytokine production is induced by the binding of CD28 or CTLA-4 to this receptor.
Gene ID
12519
Gene Name (eCommerce)
CD80 antigen
Gene Name (Vector)
CD80 antigen
Gene Symbol
Cd80
NCBI Taxonomy ID (eCommerce)
10090.0
ORF Size (aa)
921
ORF Size (bp)
921 bp
Protein Name (eCommerce)
T-lymphocyte activation antigen CD80
RefSeq ID
NM_009855
RefSeq Synonyms
NM_009855, BC145843, BC131959,
Research Areas
B-cell Receptor Signaling,Cancer,Cardiology,Cardiovascular,EGFR Signaling,EGFR Signaling in Cancer,Fc Receptor Signaling,FGF Signaling,GPCR Signaling,Host-Virus Interactions,Immunology,Innate Immunity,Interleukin Signaling,Neurobiology,NF-kB Signaling,NGF Signaling,PDGF Signaling,PI3K/Akt Signaling,PI3K-AKT Signaling in Cancer,SCF-KIT Signaling,Signal Transduction,T-cell Receptor Signaling,Toll-like Receptor Signaling
Research Areas (Faceted)
cancer,cardiovascular,immunology,infectious_disease,neurobiology,signal_transduction,stem_cell_biology
Species
mouse
Target Sentence
CD80 is a membrane receptor involved in the costimulatory signal essential for T-lymphocyte activation. T-cell proliferation and cytokine production is induced by the binding of CD28, binding to CTLA-4 has opposite effects and inhibits T-cell activation. [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/P33681].
UniGene ID
Mm.89474
UniProt ID (eCommerce)
Q00609
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.