mouse CD3E shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Mouse Cd3e.
shAAV-255006
AAV-m-CD3E-shRNA
Ready-to-use AAV expressing shRNA for silencing of Mouse Cd3e (CD3 antigen, epsilon polypeptide). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
AI504783; CD antigen CD3e; CD3; CD3epsilon; T3e; T-cell surface antigen T3/Leu-4 epsilon chain; T-cell surface glycoprotein CD3 epsilon chain
Description (eCommerce)
CD3E is the CD3-epsilon polypeptide, which together with CD3-gamma, -delta and -zeta, and the T-cell receptor alpha/beta and gamma/delta heterodimers, forms the T-cell receptor-CD3 complex. This complex plays an important role in coupling antigen recognition to several intracellular signal-transduction pathways. The epsilon polypeptide plays an essential role in T-cell development [taken from NCBI Entrez Gene (Gene ID: 916)].
Description (Vector)
The CD3 complex mediates signal transduction.
Gene ID
12501
Gene Name (eCommerce)
CD3 antigen, epsilon polypeptide
Gene Name (Vector)
CD3 antigen, epsilon polypeptide
Gene Symbol
Cd3e
NCBI Taxonomy ID (eCommerce)
10090.0
ORF Size (aa)
570
Protein Name (eCommerce)
T-cell surface glycoprotein CD3 epsilon chain
RefSeq ID
NM_007648
RefSeq Synonyms
NM_007648, BC145954, BC145926,
Research Areas
Apoptosis,Host-Virus Interactions,Immune Cells and Tumor Markers,Immunology,Immuno-Oncology,Interleukin Signaling,Neurobiology,NF-kB Signaling,Prolactin Signaling,Signal Transduction,immunology,cell_biology,T-cell Receptor Signaling
Research Areas (Faceted)
cell_biology,immuno_oncology,immunology,infectious_disease,neurobiology,signal_transduction
Species
mouse
Target Sentence
CD3E is the CD3-epsilon polypeptide, which together with CD3-gamma, -delta and -zeta, and the T-cell receptor alpha/beta and gamma/delta heterodimers, forms the T-cell receptor-CD3 complex. This complex plays an important role in coupling antigen recognition to several intracellular signal-transduction pathways. The epsilon polypeptide plays an essential role in T-cell development [taken from NCBI Entrez Gene (Gene ID: 916)].
UniGene ID
Mm.210361
UniProt ID (eCommerce)
P22646
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.