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mouse CCKBR shRNA silencing AAV

Name 
AAV-m-CCKBR-shRNA
Cat No 
shAAV-254820
Availability
4-5 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Mouse Cckbr.

shAAV-254820
AAV-m-CCKBR-shRNA

Ready-to-use AAV expressing shRNA for silencing of Mouse Cckbr (cholecystokinin B receptor). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
50
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
CCK-BR; CCK2-R; CCK2R; CCKR-2
Description (Vector)
Receptor for gastrin and cholecystokinin. The CKK-B receptors occur throughout the central nervous system where they modulate anxiety, analgesia, arousal, and neuroleptic activity. This receptor mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system|Function: Isoform 2 is constitutively activated and may regulate cancer cell proliferation via a gastrin-independent mechanism.
Gene ID
12426
Gene Name (Vector)
cholecystokinin B receptor
Gene Symbol
Cckbr
ORF Size (aa)
1359
ORF Size (bp)
1359 bp
RefSeq ID
NM_007627
RefSeq Synonyms
NM_007627, BC103538, BC103531, BC103530,
Species
mouse
UniGene ID
Mm.44513

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.