mouse CBFA2T2 shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Mouse Cbfa2t2.
shAAV-254594
AAV-m-CBFA2T2-shRNA
Ready-to-use AAV expressing shRNA for silencing of Mouse Cbfa2t2 (core-binding factor, runt domain, alpha subunit 2, translocated to, 2 (human)). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
A430091M07; C330013D05Rik; Cbfa2t2h; MTGR1
Description (Vector)
CBFA2T2 may function as a complex with the chimeric protein RUNX1/AML1-CBFA2T1/MTG8 which is produced in acute myeloid leukemia with the chromosomal translocation t(8;21). May thus be involved in the repression of AML1-dependent transcription and the induction of G-CSF/CSF3-dependent cell growth. May be a tumor suppressor gene candidate involved in myeloid tumors with the deletion of the 20q11 region.
Gene ID
12396
Gene Name (Vector)
core-binding factor, runt domain, alpha subunit 2, translocated to, 2 (human)
Gene Symbol
Cbfa2t2
ORF Size (aa)
1785
ORF Size (bp)
1785 bp
RefSeq ID
NM_172860
RefSeq Synonyms
NM_172860, NM_009823, NM_001285446, BC145679, BC138410, BC064679,
Species
mouse
UniGene ID
Mm.29914
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.