mouse CASQ1 shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Mouse Casq1.
shAAV-254568
AAV-m-CASQ1-shRNA
Ready-to-use AAV expressing shRNA for silencing of Mouse Casq1 (calsequestrin 1). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
CSQ; CSQ-1; CSQ1; sCSQ
Description (Vector)
Calsequestrin is a high-capacity, moderate affinity, calcium-binding protein and thus acts as an internal calcium store in muscle. The release of calcium bound to calsequestrin through a calcium release channel triggers muscle contraction. The skeletal muscle isoform (CASQ1) binds around 80 Ca(2+) ions, while the cardiac isoform (CASQ2) binds approximately 60 Ca(2+).
Gene ID
12372
Gene Name (Vector)
calsequestrin 1
Gene Symbol
Casq1
ORF Size (aa)
1200
ORF Size (bp)
1200 bp
RefSeq ID
NM_009813
RefSeq Synonyms
NM_009813, BC064057,
Species
mouse
UniGene ID
Mm.12829
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.