mouse CALCA shRNA silencing AAV

Name 
AAV-m-CALCA-shRNA
Cat No 
shAAV-254409
Availability
6-8 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Mouse Calca.

shAAV-254409
AAV-m-CALCA-shRNA

Ready-to-use AAV expressing shRNA for silencing of Mouse Calca (calcitonin/calcitonin-related polypeptide, alpha). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
alpha-type CGRP; CA; Calc; Calc1; calcitonin gene-related peptide 1; calcitonin gene-related peptide I; Cgrp; CGRP1; CGRP-1; CGRP-I; Ct; Ctn
Description (eCommerce)
CGRP induces vasodilation. It dilates a variety of vessels including the coronary, cerebral and systemic vasculature. Its abundance in the CNS also points toward a neurotransmitter or neuromodulator role. [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/Q99JA0].
Description (Vector)
CGRP induces vasodilation. It dilates a variety of vessels including the coronary, cerebral and systemic vasculature. Its abundance in the CNS also points toward a neurotransmitter or neuromodulator role. It also elevates platelet cAMP|Function: Calcitonin causes a rapid but short-lived drop in the level of calcium and phosphate in blood by promoting the incorporation of those ions in the bones|Function: Katacalcin is a potent plasma calcium-lowering peptide.
Gene ID
12310
Gene Name (eCommerce)
calcitonin/calcitonin-related polypeptide, alpha
Gene Name (Vector)
calcitonin/calcitonin-related polypeptide, alpha
Gene Symbol
Calca
NCBI Taxonomy ID (eCommerce)
10090.0
ORF Size (aa)
411
ORF Size (bp)
411 bp
Protein Name (eCommerce)
Calcitonin gene-related peptide 1;Calcitonin
RefSeq ID
NM_007587
RefSeq Synonyms
NM_007587, NM_001305616, NM_001289444, NM_001033954, BC030071, BC028771,
Research Areas
Aging,Cardiology,Cardiovascular,GPCR Signaling,Immunology,Neurobiology,Neurodevelopment,Signal Transduction
Research Areas (Faceted)
cardiovascular,cell_biology,developmental_biology,immunology,neurobiology,signal_transduction
Species
mouse
Target Sentence
CGRP induces vasodilation. It dilates a variety of vessels including the coronary, cerebral and systemic vasculature. Its abundance in the CNS also points toward a neurotransmitter or neuromodulator role. [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/Q99JA0].
UniGene ID
Mm.4361
UniProt ID (eCommerce)
Q99JA0

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.