mouse CACNA1D shRNA silencing AAV

Name 
AAV-m-CACNA1D-shRNA
Cat No 
shAAV-254362
Availability
6-8 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Mouse Cacna1d.

shAAV-254362
AAV-m-CACNA1D-shRNA

Ready-to-use AAV expressing shRNA for silencing of Mouse Cacna1d (calcium channel, voltage-dependent, L type, alpha 1D subunit). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
8430418G19Rik; C79217; Cach3; Cacn4; Cacnl1a2; Cav1.3; Cchl1a; Cchl1a2; D-LTCC
Description (Vector)
Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. The isoform alpha-1D gives rise to L-type calcium currents. Long-lasting (L-type) calcium channels belong to the 'high-voltage activated' (HVA) group. They are blocked by dihydropyridines (DHP), phenylalkylamines, benzothiazepines, and by omega-agatoxin-IIIA (omega-Aga-IIIA). They are however insensitive to omega-conotoxin-GVIA (omega-CTx-GVIA) and omega-agatoxin-IVA (omega-Aga-IVA).
Gene ID
12289
Gene Name (Vector)
calcium channel, voltage-dependent, L type, alpha 1D subunit
Gene Symbol
Cacna1d
ORF Size (aa)
6501
ORF Size (bp)
6501 bp
RefSeq ID
NM_028981
RefSeq Synonyms
NM_028981, NM_001302637, NM_001083616, BC172729, BC172620,
Species
mouse
UniGene ID
Mm.9772

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.