mouse PI4K2B shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Mouse Pi4k2b.
shAAV-254319
AAV-m-PI4K2B-shRNA
Ready-to-use AAV expressing shRNA for silencing of Mouse Pi4k2b (phosphatidylinositol 4-kinase type 2 beta). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
2610042N09Rik; 4933409G22Rik
Description (Vector)
Together with PI4K2A and the type III PI4Ks (PIK4CA and PIK4CB) it contributes to the overall PI4-kinase activity of the cell. This contribution may be especially significant in plasma membrane, endosomal and Golgi compartments. The phosphorylation of phosphatidylinositol (PI) to PI4P is the first committed step in the generation of phosphatidylinositol 4,5-bisphosphate (PIP2), a precursor of the second messenger inositol 1,4,5-trisphosphate (InsP3). Contributes to the production of InsP3 in stimulated cells and is likely to be involved in the regulation of vesicular trafficking.
Gene ID
67073
Gene Name (Vector)
phosphatidylinositol 4-kinase type 2 beta
Gene Symbol
Pi4k2b
ORF Size (aa)
1410
ORF Size (bp)
1410 bp
RefSeq ID
NM_025951
RefSeq Synonyms
NM_028744, NM_025951, BC062144,
Species
mouse
UniGene ID
Mm.248647
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.