mouse C1QB shRNA silencing AAV

Name 
AAV-m-C1QB-shRNA
Cat No 
shAAV-254223
Availability
6-8 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Mouse C1qb.

shAAV-254223
AAV-m-C1QB-shRNA

Ready-to-use AAV expressing shRNA for silencing of Mouse C1qb (complement component 1, q subcomponent, beta polypeptide). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Description (Vector)
C1q associates with the proenzymes C1r and C1s to yield C1, the first component of the serum complement system. The collagen-like regions of C1q interact with the Ca(2+)-dependent C1r(2)C1s(2) proenzyme complex, and efficient activation of C1 takes place on interaction of the globular heads of C1q with the Fc regions of IgG or IgM antibody present in immune complexes.
Gene ID
12260
Gene Name (Vector)
complement component 1, q subcomponent, beta polypeptide
Gene Symbol
C1qb
ORF Size (aa)
762
ORF Size (bp)
762 bp
RefSeq ID
NM_009777
RefSeq Synonyms
NM_009777, BC067001,
Species
mouse
UniGene ID
Mm.2570

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.