mouse BCO2 shRNA silencing AAV

Name 
AAV-m-BCO2-shRNA
Cat No 
shAAV-253916
Availability
6-8 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Mouse Bco2.

shAAV-253916
AAV-m-BCO2-shRNA

Ready-to-use AAV expressing shRNA for silencing of Mouse Bco2 (beta-carotene oxygenase 2). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
B-diox-II; Bcdo2; Bcmo2; CMO2
Description (Vector)
Asymmetrically cleaves beta-carotene at the 9',10' double bond resulting in the formation of beta-apo-10'-carotenal and beta-ionone. Besides beta-carotene, lycopene is also oxidatively cleaved. The apocarotenals formed by this enzyme may be the precursors for the biosynthesis of retinoic acid or exert unknown physiological effects.
Gene ID
170752
Gene Name (Vector)
beta-carotene oxygenase 2
Gene Symbol
Bco2
ORF Size (aa)
1599
ORF Size (bp)
1599 bp
RefSeq ID
NM_133217
RefSeq Synonyms
NM_133217, BC107007, BC107006,
Species
mouse
UniGene ID
Mm.390149

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.