mouse BCL2 shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Mouse Bcl2.
shAAV-253879
AAV-m-BCL2-shRNA
Ready-to-use AAV expressing shRNA for silencing of Mouse Bcl2 (B cell leukemia/lymphoma 2). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
AW986256; Bcl-2; C430015F12Rik; D630044D05Rik; D830018M01Rik
Description (Vector)
Suppresses apoptosis in a variety of cell systems including factor-dependent lymphohematopoietic and neural cells. Regulates cell death by controlling the mitochondrial membrane permeability. Appears to function in a feedback loop system with caspases. Inhibits caspase activity either by preventing the release of cytochrome c from the mitochondria and/or by binding to the apoptosis-activating factor (APAF-1).
Gene ID
12043
Gene Name (Vector)
B cell leukemia/lymphoma 2
Gene Symbol
Bcl2
ORF Size (aa)
711
RefSeq ID
NM_009741
RefSeq Synonyms
NM_177410, NM_009741, BC095964, BC068988,
Species
mouse
UniGene ID
Mm.477249
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.