mouse BANP shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Mouse Banp.
shAAV-253616
AAV-m-BANP-shRNA
Ready-to-use AAV expressing shRNA for silencing of Mouse Banp (BTG3 associated nuclear protein). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
AA408158; SMAR1
Description (Vector)
Controls V(D)J recombination during T-cell development by repressing T-cell receptor (TCR) beta enhancer function. Binds to scaffold/matrix attachment region beta (S/MARbeta), an ATC-rich DNA sequence located upstream of the TCR beta enhancer. Represses cyclin D1 transcription by recruiting HDAC1 to its promoter, thereby diminishing H3K9ac, H3S10ph and H4K8ac levels. Promotes TP53 'Ser-15' phosphorylation and nuclear accumulation, which causes cell cycle arrest (By similarity).
Gene ID
53325
Gene Name (Vector)
BTG3 associated nuclear protein
Gene Symbol
Banp
ORF Size (aa)
1647
ORF Size (bp)
1647 bp
RefSeq ID
NM_016812
RefSeq Synonyms
NM_016812, NM_001285983, NM_001285981, NM_001110100, BC062641, BC022168, BC021650,
Species
mouse
UniGene ID
Mm.287163
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.