mouse BANF1 shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Mouse Banf1.
shAAV-253613
AAV-m-BANF1-shRNA
Ready-to-use AAV expressing shRNA for silencing of Mouse Banf1 (barrier to autointegration factor 1). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
Baf; Bcrp1; L2bp1/Baf
Description (Vector)
Plays fundamental roles in nuclear assembly, chromatin organization, gene expression and gonad development. May potently compress chromatin structure and be involved in membrane recruitment and chromatin decondensation during nuclear assembly. Contains 2 non-specific dsDNA-binding sites which may promote DNA cross-bridging. Exploited by retroviruses for inhibiting self-destructing autointegration of retroviral DNA, thereby promoting integration of viral DNA into the host chromosome. EMD and BAF are cooperative cofactors of HIV-1 infection. Association of EMD with the viral DNA requires the presence of BAF and viral integrase. The association of viral DNA with chromatin requires the presence of BAF and EMD.
Gene ID
23825
Gene Name (Vector)
barrier to autointegration factor 1
Gene Symbol
Banf1
ORF Size (aa)
270
RefSeq ID
NM_011793
RefSeq Synonyms
NM_011793, NM_001286608, NM_001038231, BC003709,
Species
mouse
UniGene ID
Mm.358649
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.