human FNIP1 Over-expression AAV

Name
AAV-h-FNIP1

Cat No
AAV-209210

Availability
4-5 weeks

This is an AAV expressing Human FNIP1.

AAV-209210

AAV-h-FNIP1

Ready-to-use AAV expressing Human FNIP1 (folliculin interacting protein 1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

CMV (default), or choose from 30 different ubiquitous or cell specific promoter

Reporter

none, optional GFP, CFP, YFP, RFP or mCherry

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

folliculin-interacting protein 1

Description (eCommerce)

Folliculin-interacting protein 1 (FNIP1) binds to the tumor suppressor protein folliculin and to AMP-activated protein kinase (AMPK). FNIP1 participates in the regulation of cellular metabolism and nutrient sensing by modulating the AMPK and target of rapamycin signaling pathways. FNIP1 has a closely related paralog that encodes a protein with similar binding activities. Both related proteins also associate with the molecular chaperone heat shock protein-90 (Hsp90) and negatively regulate its ATPase activity and facilitate its association with folliculin [taken from NCBI Entrez Gene (Gene ID: 96459)].

Gene ID

96459

Gene Name (eCommerce)

folliculin interacting protein 1

Gene Name (Vector)

folliculin interacting protein 1

Gene Symbol

FNIP1

HGNC ID

HGNC:29418

NCBI Taxonomy ID (eCommerce)

9606.0

ORF Size (aa)

3498

ORF Size (bp)

3498 bp

Protein Name (eCommerce)

Folliculin-interacting protein 1

RefSeq ID

NM_133372

RefSeq Synonyms

NM_133372, NM_001346114, NM_001346113, NM_001008738, BC172496, BC156495, BC001956,

Research Areas

Cell Biology

Research Areas (Faceted)

cell_biology

Species

human

Target Sentence

Folliculin-interacting protein 1 (FNIP1) binds to the tumor suppressor protein folliculin and to AMP-activated protein kinase (AMPK). FNIP1 participates in the regulation of cellular metabolism and nutrient sensing by modulating the AMPK and target of rapamycin signaling pathways. FNIP1 has a closely related paralog that encodes a protein with similar binding activities. Both related proteins also associate with the molecular chaperone heat shock protein-90 (Hsp90) and negatively regulate its ATPase activity and facilitate its association with folliculin [taken from NCBI Entrez Gene (Gene ID: 96459)].

UniGene ID

Hs.591273

UniProt ID (eCommerce)

Q8TF40

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.