mouse PPP2R2B shRNA silencing AAV

Name 
AAV-m-PPP2R2B-shRNA
Cat No 
shAAV-253401
Availability
6-8 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Mouse PPP2R2B.

shAAV-253401
AAV-m-PPP2R2B-shRNA

Ready-to-use AAV expressing shRNA for silencing of Mouse PPP2R2B (protein phosphatase 2, regulatory subunit B, beta). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
2900026H06Rik; 6330404L05Rik; E130009M08Rik; PP2A-PR55B; PR55-BETA; SCA12
Description (Vector)
The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. Within the PP2A holoenzyme complex, isoform 2 is required to promote proapoptotic activity (By similarity). Isoform 2 regulates neuronal survival through the mitochondrial fission and fusion balance (By similarity).
Gene ID
72930
Gene Name (Vector)
protein phosphatase 2, regulatory subunit B, beta
Gene Symbol
PPP2R2B
ORF Size (aa)
1341
ORF Size (bp)
1341 bp
RefSeq ID
NM_028392
RefSeq Synonyms
NM_028392, NM_027531, BC088979, BC026686,
Species
mouse
UniGene ID
Mm.26134

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.