mouse ASGR2 shRNA silencing AAV

Name 
AAV-m-ASGR2-shRNA
Cat No 
shAAV-253153
Availability
6-8 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Mouse Asgr2.

shAAV-253153
AAV-m-ASGR2-shRNA

Ready-to-use AAV expressing shRNA for silencing of Mouse Asgr2 (asialoglycoprotein receptor 2). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
ASGPR2; Asgr; Asgr-2; HL-2
Description (Vector)
Mediates the endocytosis of plasma glycoproteins to which the terminal sialic acid residue on their complex carbohydrate moieties has been removed. The receptor recognizes terminal galactose and N-acetylgalactosamine units. After ligand binding to the receptor, the resulting complex is internalized and transported to a sorting organelle, where receptor and ligand are disassociated. The receptor then returns to the cell membrane surface.
Gene ID
11890
Gene Name (Vector)
asialoglycoprotein receptor 2
Gene Symbol
Asgr2
ORF Size (aa)
906
ORF Size (bp)
906 bp
RefSeq ID
NM_007493
RefSeq Synonyms
NM_007493, NM_001313927, NM_001313926, NM_001313925, BC011197,
Species
mouse
UniGene ID
Mm.1357

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.